Гл.ас. д-р Христина Лазарова
Assistant Professor Hristina Lazarova, PhD
Институт по минералогия и кристалография "Акад. Иван Костов" - Българска академия на науките
Institute of Mineralogy and Crystallography "Acad. Ivan Kostov" - Bulgarian Academy of Sciences
CURRICULUM VITAE:
Place of birth: Parvomay, Bulgaria
Date of birth: 12.08.1981
Nationality: Bulgarian
EDUCATION AND ACADEMIC DEGREES OBTAINED:
2021 - PhD, Institute of Organic Chemistry with Centre of Phytochemistry",
Bulgarian Academy of Sciences
2010 - Master degree in Medical Chemistry, Sofia University “St. Kliment Ohridski”, Sofia
ACADEMIC POSITIONS IN THE LAST FIVE YEARS
2022 – currently, Assistant Professor, Institute of Mineralogy and
Crystallography, Acad. Ivan Kostov", Bulgarian Academy of Sciences
(IMC-BAS)
FIELD OF INTEREST:
– Synthesis of micro/mesoporous and nanostructured oxides.
– Physicochemical characterization of modified materials
(temperature gravimetrical analysis, temperature programmed reduction, infrared
spectroscopy, UV-VIS spectroscopy, adsorption methods etc.).
– Investigation of catalytic properties of modified nanocomposite
materials: Catalytic combustion of different volatile organic compounds (VOCs)
for environmental protection;
– Investigation of the relation between catalyst composition,
structure and catalytic behaviour.
– Genesis of the catalytic sites and mechanism of the catalytic
processes.
– Preparation of new drug delivery systems on the basis of
mesoporous silicas with different structure, morphology, particle size and
surface functionality.
– Study on the optimization
of the loading capacity and release properties of loaded drugs -antibiotics,
glucocorticoids, anti-inflammatory non-steriods and antioxidants.
LIST OF SELECTED PUBLICATIONS AND PATENTS:
1. Petrova, A., Popova, M., Kuzmanova, Ch.,
Tsvetkova, I., Naydensk, H., Muli, E., Bankova, V.. New biologically active
compounds from Kenyan propolis. Fitoterapia, 81, 2010, 509-514.
2. Popova, M., Szegedi, Á., Lazarova, H., Ristić,
A., Kalvachev, Y., Atanasova, G., Wilde, N., Tušar, N.N., Gläser, R.. Synthesis
of biomass derived levulinate esters on novel sulfated Zr/KIL-2 composite
catalysts. Microporous and Mesoporous Materials, 235, 2016, DOI:10.1016/j.micromeso.2016.07.047,
50-58.
3. Todorova,T., Kalvachev,Y., Lazarova,H.,
Popova,M.. Catalytic activity of modified mordenite in the reaction of m-xylene
transformation. Comptes Rendus de L'Academie Bulgare des Sciences, 69, 2016,
1283-1290.
4. Popova, M., Lazarova, H., Kalvachev, Y.,
Todorova, T., Szegedi, Á., Shestakova, P., Mali, G., Dasireddy, V. D. B. C.,
Likozar, B.. Zr-modified hierarchical mordenite as heterogeneous catalyst for
glycerol esterification. Catalysis Communications, 100, 2017,
DOI:10.1016/j.catcom.2017.06.009, 10-14.
5. Popova, M., Lazarova, H., Szegedi, A., Mihályi,
M. R., Rangus, M., Likozar, B., Dasireddy, V.D.B.C. Renewable glycerol
esterification over sulfonic-modified mesoporous silicas. J. Serb. Chem. Soc.,
82, 2017, DOI:doi.org/10.2298/JSC170306071P, 1-12.
6. Popova,
M., Szegedi, Á., Lazarova, H., Dimitrov, M., Kalvachev, Y., Atanasova, G.,
Ristić, A., Wilde, N., Gläser, R.. Influence of the preparation method of
sulfated zirconia nanoparticles for levulinic acid esterification. Reaction
Kinetics, Mechanisms and Catalysis, 120, 1, Springer Nature, 2017,
DOI:10.1007/s11144-016-1088-4, 55-67.
7. Kalvachev,Y., Todorova,T., Nihtianova,D.,
Lazarova,H., Popova,M.. Fluoride etching of mordenite and its influence on
catalytic activity. 51, Journal of Materials Science, 2017, DOI:10.1007/s10853-017-0769-3,
1-12.
8. Vicente, A., Coelho, J., Simeonov, S., Lazarova,
H., Popova, M., Afonso, C.. Oxidation of 5-Chloromethylfurfural (CMF) to
2,5-Diformylfuran (DFF). Molecules, 22, 2, 2017, DOI:10.3390/molecules22020329
9. Lazarova,H., Popova,M., Szegedi,A., Likozar,B.,
Dasireddy,V., Novak-Tusar,N.. Levulinic acid esterification on SO3H-modified
mesoporous silicas. Bulgarian Chemical Communications, 50, Special issue H,
Bulgarian Chemical Communications, 2018, 56-60.
10. Popova, M., Lazarova, H., Trusheva, B., Popova,
M., Bankova, V., Mihály, J., Najdenski, H., Tsvetkova, I., Szegedi, Á..
Nanostructured silver silica materials as potential propolis carriers.
Microporous and Mesoporous Materials, 263, 2018,
DOI:10.1016/j.micromeso.2017.11.043., 28-33.
11. Popova, M., Shestakova, P., Lazarova, H.,
Dimitrov, M., Kovacheva, D., Szegedi, A., Mali, G., Dasireddy, V., Likozar, B.,
Wilde, N., Gläser, R.. Efficient solid acid catalysts based on sulfated tin
oxides for liquid phase esterification of levulinic acid with ethanol. Applied
Catalysis A: General, 560, Elsevier B.V., 2018, DOI:https://doi.org/10.1016/j.apcata.2018.04.041,
119-131.
12. Popova, M., Djinović, P., Ristić, A.,
Lazarova,H., Dražić, G., Pintar, A., Balu, A.M., Tušar, Nataša Novak..
Vapor-Phase Hydrogenation of Levulinic Acid to γ-valerolactone Over
Bi-Functional Ni/HZSM-5 Catalyst. Frontiers in Chemistry, 6, 2018,
DOI:10.3389/fchem.2018.00285
13. Popova,M., Lazarova,H., Szegedi,A.,
Mihályi,M.R., Rangus,M., Likozar,B., Dasireddy, V.D.B.C.. Renewable glycerol
esterification over sulfonic-modified mesoporous silicas. 83, 1, Journal of the
Serbian Chemical Society, 2018, DOI:10.2298/JSC170306071P, 39-50
14. Popova,M., Mihaylova,R., Momekov,G.,
Momekova,D., Lazarova, H, Trendafilova,I., Mitova,V., Koseva,N., Mihályi,J.,
Shestakova,P., St. Petkov,P., Aleksandrov,H.A., Vayssilov,Georgi N.,
Konstantinov,S., Szegedi,Á.. Verapamil delivery systems on the basis of
mesoporous ZSM-5/KIT-6 and ZSM-5/SBA-15 polymer nanocomposites as a potential
tool to overcome MDR in cancer cells. European Journal of Pharmaceutics and
Biopharmaceutics, 142, 2019, DOI:10.1016/j.ejpb.2019.07.021, 460-472
15. Simeonov, S., Lazarova, H., Marinova, M., Popova,
M.. Achmatowicz rearrangement enables hydrogenolysis-free gas-phase synthesis
of pentane-1,2,5-triol from furfuryl alcohol. Green Chemistry, 21, 2019,
DOI:10.1039/C9GC02888A, 5657-5664.
16. Boycheva, S., Zgureva, D., Václavíková, M.,
Kalvachev,Y., Lazarova,H., Popova, M.. Studies on non-modified and
copper-modified coal ash zeolites as heterogeneous catalysts for VOCs
oxidation. Journal of Hazardous Materials, 361, 2019,
DOI:10.1016/j.jhazmat.2018.07.020, 374-382
17. Pardo Cuervo,O.H., Simeonov,S.P., Peixoto,A.F.,
Popova,M.D., Lazarova,H.I., Romanelli,G.P., Martínez,J.J., Freire,C.,
Afonso,C.A.M.. Efficient Continuous Production of the Biofuel Additive
5-(t-Butoxymethyl) Furfural from 5-Hydroxymethylfurfural. Energy Technology, 7,
11, 2019, DOI:10.1002/ente.201900780,
18. Pavlovic, J., Popova, M., Mihalyi, R.M., Mazaj,
M., Mali, G., Kovač, J., Lazarova,H., Rajic, N.. Catalytic activity of SnO2-
and SO4/SnO2-containing clinoptilolite in the esterification of levulinic acid.
Microporous and Mesoporous Materials, 279, 2019,
DOI:10.1016/j.micromeso.2018.12.009, 10-18.
19. Popova, M., Koseva, N., Trendafilova, I.,
Lazarova, H., Mitova, V., Mihály, J., Momekova, D., Momekov, G., Koleva, I.,
Aleksandrov, H., Vayssilov, G., Szegedi , A.. Tamoxifen Delivery System Based
on PEGylated Magnetic MCM-41 Silica. Molecules, 25, 21, 2020, DOI:https://doi.org/10.3390/molecules25215129
20. Popova,M., Boycheva,S., Lazarova,H, Zgureva,D.,
Lázár,K., Szegedi,Á.. VOC oxidation and CO2 adsorption on dual
adsorption/catalytic system based on fly ash zeolites. Catalysis Today, 357,
2020, DOI:10.1016/j.cattod.2019.06.070, 518-525.
21. Trendafilova, I., Mihaly, J., Momekova, D.,
Chimshirova, R., Lazarova, H., Momekov, G., Popova, M.. Antioxidant activity
and modified release profiles of morin and hesperetin flavonoids loaded in Mg-
or Ag-modified SBA-16 carriers. Materials Today Communications, 24, Article
number 10119, 2020,
22. Boycheva,S., Zgureva,D., Lazarova,H.,
Lazarova,K., Popov,C., Babeva,T., Popova,M.. Processing of high-grade zeolite
nanocomposites from solid fuel combustion by-products as critical raw materials
substitutes. Manufacturing Review, 7, Article number 22, 2020,
DOI:10.1051/mfreview/2020019
23. Boycheva,S., Zgureva,D., Lazarova,K., Babeva,T.,
Popov,C., Lazarova,H., Popova,M.. Progress in the utilization of coal fly ash
by conversion to zeolites with green energy applications. Materials, 13, 9,
2020, DOI:10.3390/MA13092014,
24. Todorova, T., Shestakova, P., Petrova, T.,
Popova, M., Lazarova, H., Kalvachev, Y.. Fluoride etching of AlZSM-5 and
GaZSM-5 zeolites. Journal of Materials Science, 28, 55, Springer, 2020,
DOI:10.1007/s10853-020-05030-6, 13799-13814.
25. Popova, M., Koseva, N., Trendafilova, I.,
Lazarova, H., Mitova, V., Mihály, J., Momekova, D., Konstantinov, S., Koleva,
I., Petkov, P., Vayssilov, G., Aleksandrov, H., Szegedi, A.. Design of
PEG-modified magnetic nanoporous silica based miltefosine delivery system:
Experimental and theoretical approaches. Microporous and Mesoporous Materials,
310, 2021, DOI:https://doi.org/10.1016/j.micromeso.2020.110664, 110664.
26. Popova, M., Szegedi, A., Oykova, M., Lazarova,
H., Koseva, N., Mihályi, M.R., Mitrev, Y., Shestakova, P..
Hydrodemethoxylation/Dealkylation on Bifunctional Nanosized Zeolite Beta.
Molecules, 26, 24, 2021,
27. Popova,M., Szegedi,Á., Oykova,M., Lazarova,H.,
Koseva,N., Mihályi,M.R., Shestakova,P.. Selective production of phenol on
bifunctional, hierarchical zsm-5 zeolites. Molecules, 26, 12, 2021,
DOI:10.3390/molecules26123576,
28. Ravutsov, M., Mitrev,Y., Shestakova,P.,
Lazarova,H., Simeonov,S., Popova,M.. CO2 Adsorption on Modified Mesoporous
Silicas: The Role of the Adsorption Sites. Nanomaterials, 11, 11, 2021,
DOI:https://doi.org/10.3390/nano11112831,
29. Shestakova, P., Popova, M., Szegedi, A.,
Lazarova, H., Luong, T. K. N., Trendafilova, I., Mihály, J., Parac-Vogt, T. N..
Hybrid catalyst with combined Lewis and Brønsted acidity based on ZrIV
substituted polyoxometalate grafted on mesoporous MCM-41 silica for
esterification of renewable levulinic acid. Microporous and Mesoporous
Materials, 323, 2021, 111203
30. Trendafilova, I., Lazarova, H., Chimshirova, R.,
Trusheva, B., Koseva, N., Popova, M.. Novel kaempferol delivery systems based
on Mg-containing MCM-41 mesoporous silicas. Journal of Solid State Chemistry,
301, Elsevier, 2021, DOI:10.1016/j.jssc.2021.122323, 122323
31. Boycheva,S., Zgureva,D., Lazarova,H., Popova,M..
Comparative studies of carbon capture onto coal fly ash zeolites Na-X and Na–Ca-X.
Chemosphere, 271, 2021, DOI:10.1016/j.chemosphere.2020.129505
32. Žumbar,T., Ristić ,A., Dražić, G., Lazarova, H.,
Volavšek, J., Pintar,A., Logar,N.Z., Tušar, N.N.. Influence of alumina
precursor properties on cu-fe alumina supported catalysts for total toluene
oxidation as a model volatile organic air pollutant. Catalysts, 11, 2, 2021,
DOI:10.3390/catal11020252